Human Osteoarthritic model
B-CULTURE Osteoarthritic model uses human samples integrating cartilage and subchondral bone to model the two phenotypic regions of the disease creating two environments in a single dual-chamber.
Angiogenisis process in osteoarthritis
Inflammation and vascularization are related to osteoarthritic conditions and essential for a healthy knee joint. B-CULTURE technology enables the screening of molecules to assess vascularization inhibition and stimulation in controllable 3D in vitro model.
Raphaël F. Canadas, Tanchen Ren, Alexandra P. Marques, Joaquim M. Oliveira, Rui L. Reis, and Utkan Demirci
Adv. Funct. Mater. 2018, 28, 1804148
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