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Osteoarthritic model

Human Osteoarthritic model

B-CULTURE Osteoarthritic model uses human samples integrating cartilage and subchondral bone to model the two phenotypic regions of the disease creating two environments in a single dual-chamber.

Angiogenisis process in osteoarthritis

Inflammation and vascularization are related to osteoarthritic conditions and essential for a healthy knee joint. B-CULTURE technology enables the screening of molecules to assess vascularization inhibition and stimulation in controllable 3D in vitro model.



Biochemical Gradients to Generate 3D_RFC

Raphaël F. Canadas, Tanchen Ren, Alexandra P. Marques, Joaquim M. Oliveira, Rui L. Reis, and Utkan Demirci

Adv. Funct. Mater. 2018, 28, 1804148


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